This advanced joint supplement uses UC-II, an innovative ingredient that works with the immune system to help soothe, comfort and support joint structure. Unlike commonly used joint supplements, UC-II has a unique mode of action and has shown positive results in clinical studies for both dogs and humans. The multi-action formula also contains glucosamine, omega 3 and vitamin E, making it particularly well suited to stiff or senior dogs. Simply give one chew a day regardless of your dog's size, with no loading period needed.